产品简介　

 NFkB （DNA binding factor KBF2;  H2TF1; ; NFKB-p52; Lymphocyte translocation chromosome 10; Lyt 10; Lyt10; NFKB2; Nuclear factor NF kappa B p100 subunit; Nuclear factor NF kappa B p52 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 2; Oncogene Lyt 10; p49/p100.）is formed through the association of multiple subunits, either as a homodimer or heterodimer. Subunits have been identified as p50 (NFkB1), p65 (RelA), c-Rel, RelB and p52 (NFkB2). The classic NFkB form exists as a p50-p65 heterodimer and predominates in many cell types. Many of the possible combinatorial forms of homo- and heterodimers have been identified and growing evidence indicates that different forms of NFkB have different functions in cells. Interestingly, both the p50 and p52 subunits are derived from the precursor proteins p105 and p100 respectively, that each contain multiple copies of the so called ankyrin repeat at their C termini. Nuclear translocation of NFkB is confirmed by the use of electrophorectic mobility shift assays or by immunoblotting with nuclear extracts. The subunit composition of NFkB is confirmed by the use of antibodies that "supershift" the DNA/protein complex.
    NF-κB2多肽(NF-κB2 Polypeptide)为本所人工合成并纯化的NF-κB2的多肽片段，本品为干粉或水溶液。
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保存条件                                                        

在-20℃或以下可保存1年或以上。使用过程中可短时间保存于4℃。请勿反复冻融或于0℃以上久置。