手机:13552878684 电话:8610-6233 1192 QQ号:2216266870
站内搜索:
您目前所在的位置:首页 >> 产品目录 >> 人工抗原 >> 多肽及其偶联物
产品搜索:
Ring-box 1多肽

产品编号

包装

价格

3710059-R

0.5mg

680.00

3710059-R1

1mg

1280.00

3710059-R2

2mg

1980.00

产品简介

         E3 ubiquitin ligase component of multiple cullin-RING- based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins, including proteins involved in cell cycle progression, signal transduction, transcription and transcription-coupled nucleotide excision repair. The functional specificity of the E3 ubiquitin-protein ligase complexes depends on the variable substrate recognition components. As a component of the CSA complex promotes the ubiquitination of ERCC6 resulting in proteasomal degradation. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme, like CDC34, to the complex and brings it into close proximity to the substrate. Probably also stimulates CDC34 autoubiquitination. May be required for histone H3 and histone H4 ubiquitination in response to ultraviolet and for subsequ. Ring-box 1 (RBX1) encodes an evolutionarily conserved protein that interacts with cullins. The protein plays a unique role in the ubiquitination reaction by heterodimerizing with cullin-1 to catalyze ubiquitin polymerization. It also may be involved in the regulation of protein turn-over.

Ring-box 1多肽 (Ring-box 1PolypeptideRBX1) 为本所人工合成并纯化的Ring-box 1多肽片段,本品为干粉或水溶液。

包装

   产品编号

3710059-R

3710059-R1

3710059-R2

Ring-box 1多肽

0.5mg

1mg

2mg

说明书

1 份

保存                                                        

-20℃或以下可保存1年或以上。使用过程中可短时间保存于4℃。请勿反复冻融或于0℃以上久置。

 

更新时间:2016-05-12    浏览次数:173次
Copyright@2009 北京翰谱医药生物研究所 All Rights Reserved
手机:13552878684 电话:8610-6233 1192 QQ号:2216266870 E-mail:hapmed@163.com 地址:北京市昌平区沙河镇昌平路97号新元科技园5幢5-542 京ICP备09031681号
京ICP备2010042718号 技术支持:才高八斗 网站在线客服
网站在线客服